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1

Na+-Glucose Cotransporter (SGLT) Inhibitors as Antidiabetic Agents. 4. Synthesis and Pharmacological Properties of 4‘-Dehydroxyphlorizin Derivatives Substituted on the B Ring

Tsujihara, Kenji, Hongu, Mitsuya, Saito, Kunio, Kawanishi, Hiroyuki, Kuriyama, Kayoko, Matsumoto, Mamoru, Oku, Akira, Ueta, Kiichiro, Tsuda, Minoru, Saito, Akira

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 481 KB

english, 1999

2

CHARACTERISTICS FROM DRAWINGS AND PRESENT CONDITIONS OF TOYOHARA FACTORY BUILDINGS AND HOUSES CONSTRUCTED BY KARAFUTO SUGAR: A COMPARISON WITH THE SHIBETSU FACTORY CONSTRUCTED BY MEIJI SUGAR

TSUJIHARA, Makihiko, KAKU, Satoru, IMAMURA, Satomi

Journal:

AIJ Journal of Technology and Design

Year:

2015

File:

PDF, 2.06 MB

2015

3

T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes

Oku, A., Ueta, K., Arakawa, K., Ishihara, T., Nawano, M., Kuronuma, Y., Matsumoto, M., Saito, A., Tsujihara, K., Anai, M., Asano, T., Kanai, Y., Endou, H.

Journal:

Year:

1999

Language:

english

File:

PDF, 549 KB

english, 1999

4

RESTORATION OF THE COMPANY TOWN PLAN CONSTRUCTED BY THE CHOSEN CHISSO HIRYO HUNGNAM FACTORY

TSUJIHARA, Makihiko

Journal:

Journal of Architecture and Planning (Transactions of AIJ)

Year:

2012

Language:

english

File:

PDF, 2.99 MB

english, 2012

5

ChemInform Abstract: Synthesis of Taxoids. Part 1. Regioselective Lewis Acid Mediated Ring- Opening of Aryl Orthoacetates.

N. HARADA, T. HASHIYAMA, K. OZAKI, T. YAMAGUCHI, A. ANDO, K. TSUJIHARA

Journal:

Year:

1997

File:

PDF, 30 KB

1997

6

ChemInform Abstract: Synthesis and Antitumor Activity of Quaternary Salts of 2-(2′- Oxoalkoxy)-9-hydroxyellipticines.

N. HARADA, T. KAWAGUCHI, I. INOUE, M. OHASHI, K. ODA, T. HASHIYAMA, K. TSUJIHARA

Journal:

Year:

1997

File:

PDF, 30 KB

1997

7

ChemInform Abstract: Synthesis and Antitumor Activity of 9-Acyloxyellipticines.

N. HARADA, K. OZAKI, K. ODA, N. NAKANISHI, M. OHASHI, T. HASHIYAMA, K. TSUJIHARA

Journal:

Year:

1997

File:

PDF, 27 KB

1997

8

ChemInform Abstract: Synthesis of Taxoids. Part 2. Synthesis and Antitumor Activity of Water-Soluble Taxoids.

N. HARADA, K. OZAKI, T. YAMAGUCHI, H. ARAKAWA, A. ANDO, K. ODA, N. NAKANISHI, M. OHASHI, T. HASHIYAMA, K. TSUJIHARA

Journal:

Year:

1998

File:

PDF, 29 KB

1998

9

ChemInform Abstract: Na+-Glucose Cotransporter Inhibitors as Antidiabetic Agents. Part 2. Synthesis and Structure—Activity Relationships of 4′-Dehydroxyphlorizin Derivatives.

M. HONGU, T. TANAKA, N. FUNAMI, K. SAITO, K. ARAKAWA, M. MATSUMOTO, K. TSUJIHARA

Journal:

Year:

1998

File:

PDF, 39 KB

1998

10

ChemInform Abstract: Na+-Glucose Cotransporter Inhibitors as Antidiabetic Agents. Part 3. Synthesis and Pharmacological Properties of 4′-Dehydroxyphlorizin Derivatives Modified at the OH Groups of the Glucose Moiety.

Mitsuya Hongu, Nobuyuki Funami, Youichi Takahashi, Kunio Saito, Kenji Arakawa, Mamoru Matsumoto, Hirokazu Yamakita, Kenji Tsujihara

Journal:

Year:

1999

File:

PDF, 42 KB

1999

11

ChemInform Abstract: Stereoselective Synthesis of Antifungal Sulfoximines, Novel Triazoles. Part 1.

Hiroyuki Kawanishi, Hiroshi Morimoto, Takao Nakano, Tadatoshi Miyajima, Kuniyuki Oda, Katsuo Takeda, Shigeru Yano, Naomitsu Hirano, Kenji Tsujihara

Journal:

Year:

1999

File:

PDF, 29 KB

1999

12

ChemInform Abstract: Stereoselective Synthesis of Antifungal Sulfoximines, Novel Triazoles. Part 2.

Hiroyuki Kawanishi, Hiroshi Morimoto, Takao Nakano, Tatsuya Watanabe, Kuniyuki Oda, Kenji Tsujihara

Journal:

Year:

1999

File:

PDF, 34 KB

1999

13

ChemInform Abstract: Synthesis of Taxoids. Part 5. Synthesis and Evaluation of Novel Water-Soluble Prodrugs of a 3′-Desphenyl-3′-cyclopropyl Analogue of Docetaxel.

Tetsuo Yamaguchi, Naoyuki Harada, Kunihiko Ozaki, Hiroaki Arakawa, Kouji Oda, Noriyuki Nakanishi, Kenji Tsujihara, Tomiki Hashiyama

Journal:

Year:

1999

File:

PDF, 37 KB

1999

14

ChemInform Abstract: Solid-Liquid Phase Transfer Catalyzed Novel Glycosylation Reaction of Phenols.

Mitsuya Hongu, Kunio Saito, Kenji Tsujihara

Journal:

Year:

1999

File:

PDF, 27 KB

1999

15

ChemInform Abstract: Na+-Glucose Cotransporter (SGLT) Inhibitors as Antidiabetic Agents. Part 4. Synthesis and Pharmacological Properties of 4′-Dehydroxyphlorizin Derivatives Substituted on the B Ring.

Kenji Tsujihara, Mitsuya Hongu, Kunio Saito, Hiroyuki Kawanishi, Kayoko Kuriyama, Mamoru Matsumoto, Akira Oku, Kiichiro Ueta, Minoru Tsuda, Akira Saito

Journal:

Year:

2000

File:

PDF, 32 KB

2000

16

ChemInform Abstract: PdII/PdIV Catalytic Enantioselective Synthesis of Bicyclo[3.1.0]hexanes via Oxidative Cyclization of Enynes.

Tetsuya Tsujihara, Kazuhiro Takenaka, Kiyotaka Onitsuka, Minoru Hatanaka, Hiroaki Sasai

Journal:

Year:

2009

File:

PDF, 28 KB

2009

17

ChemInform Abstract: Enantioselective Intramolecular Oxidative Aminocarbonylation of Alkenylureas Catalyzed by Palladium—Spiro Bis(isoxazoline) Complexes.

Tetsuya Tsujihara, Toshio Shinohara, Kazuhiro Takenaka, Shinobu Takizawa, Kiyotaka Onitsuka, Minoru Hatanaka, Hiroaki Sasai

Journal:

Year:

2010

File:

PDF, 56 KB

2010

18

Augmentation of tumor immunity by 6-mpg, a water-soluble derivative of 6-mercaptopurine, in mice

Tatsuo Kashida, Naoko Narasaki, Kenji Tsujihara, Kazuaki Naito, Shigeyuki Takeyama

Journal:

International Journal of Immunopharmacology

Year:

1996

Language:

english

File:

PDF, 589 KB

english, 1996

19

An improved solar neutron telescope installed at a very high altitude in México

J.F. Valdés-Galicia, Y. Muraki, H. Tsujihara, T. Sako, O. Musalem, A. Hurtado, L.X. González, Y. Matsubara, K. Watanabe, N. Hirano, N. Tateiwa, S. Shibata, T. Sakai

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2004

Language:

english

File:

PDF, 1.01 MB

english, 2004

20

Optical resolution of tetra isopropyl-substituted spiro bis(isoxazoline)i-Pr-SPRIX

Shinobu Takizawa, Junichi Yogo, Tetsuya Tsujihara, Kiyotaka Onitsuka, Hiroaki Sasai

Journal:

Journal of Organometallic Chemistry

Year:

2007

Language:

english

File:

PDF, 233 KB

english, 2007

21

Design and synthesis of chiral hybrid spiro (isoxazole–isoxazoline) ligands

Priti S. Koranne, Tetsuya Tsujihara, Midori A. Arai, Gan B. Bajracharya, Takeyuki Suzuki, Kiyotaka Onitsuka, Hiroaki Sasai

Journal:

Tetrahedron: Asymmetry

Year:

2007

Language:

english

File:

PDF, 214 KB

english, 2007

22

Divergent synthesis of chiral spiro (isoxazole–isoxazoline) hybrid ligands

Kazuhiro Takenaka, Shuhei Nakatsuka, Tetsuya Tsujihara, Priti S. Koranne, Hiroaki Sasai

Journal:

Tetrahedron: Asymmetry

Year:

2008

Language:

english

File:

PDF, 445 KB

english, 2008

23

Pyrolysis of N-p-toluenesulphonylsulphilimines

K. Tsujihara, N. Furukawa, S. Oae

Journal:

Year:

1971

Language:

english

File:

PDF, 595 KB

english, 1971

24

The reaction of N-sulfonyl sulfilimine with cyanide ion in DMSO

S. Oae, T. Aida, K. Tsujihara, N. Furukawa

Journal:

Tetrahedron Letters

Year:

1971

Language:

english

File:

PDF, 202 KB

english, 1971

25

The alkaline alcoholysis of N-p-toluenesulfonyl sulfilimine

Haruyo Kobayashi, Naomichi Furukawa, Tetsuo Aida, Kenji Tsujihara, Shigeru Oae

Journal:

Tetrahedron Letters

Year:

1971

Language:

english

File:

PDF, 183 KB

english, 1971

26

The elimination reaction of N-sulfonylsulfilimine

S. Oae, K. Tsujihara, N. Furukawa

Journal:

Tetrahedron Letters

Year:

1970

Language:

english

File:

PDF, 182 KB

english, 1970

27

Study on the mechanism of immunopotentiating antitumor effect of 6-MPG, a water-soluble derivative of 6-mercaptopurine

Tatsuo Kashida, Naoko Narasaki, Atsuko Sakai, Kenji Tsujihara, Kei Tsuzurahara, Kazuaki Naito, Shigeyuki Takeyama

Journal:

Immunopharmacology

Year:

1997

Language:

english

File:

PDF, 438 KB

english, 1997

28

Critical current density of the Y-Ba-Cu-O superconducting filament produced by suspension spinning method

Tomoko Goto, Iwao Horiba, Masahiro Kada, Masanori Tsujihara

Journal:

Physica C: Superconductivity

Year:

1988

Language:

english

File:

PDF, 465 KB

english, 1988

29

Synthesis of taxoids 5. Synthesis and evaluation of novel water-soluble prodrugs of a 3′-desphenyl-3′-cyclopropyl analogue of docetaxel

Tetsuo Yamaguchi, Naoyuki Harada, Kunihiko Ozaki, Hiroaki Arakawa, Kouji Oda, Noriyuki Nakanishi, Kenji Tsujihara, Tomiki Hashiyama

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 400 KB

english, 1999

30

Wet spinning of a single layered perovskite Y-Ba-Cu-O superconductor

Tomoko Goto, Masanori Tsujihara

Journal:

Journal of Materials Science Letters

Year:

1988

Language:

english

File:

PDF, 547 KB

english, 1988

31

Improving cache attacks by considering cipher structure

Yukiyasu Tsunoo, Etsuko Tsujihara, Maki Shigeri, Hiroyasu Kubo, Kazuhiko Minematsu

Journal:

International Journal of Information Security

Year:

2006

Language:

english

File:

PDF, 706 KB

english, 2006

32

Protective effects of lemon flavonoids on oxidative stress in diabetic rats

Yoshiaki Miyake, Kanefumi Yamamoto, Nobuko Tsujihara, Toshihiko Osawa

Journal:

Year:

1998

Language:

english

File:

PDF, 558 KB

english, 1998

33

The stereochemistry of Ei reaction of N-p-toluenesulphonyl sulphilimines

K. Tsujihara, K. Harada, N. Furukawa, S. Oae

Journal:

Year:

1971

Language:

english

File:

PDF, 501 KB

english, 1971

34

Sulfilimine and Sulfoximine VI The reaction of N-sulfonylsulfilimine with sulfoxide

K. Tsujihara, T. Aida, N. Furukawa, S. Oae

Journal:

Tetrahedron Letters

Year:

1970

Language:

english

File:

PDF, 161 KB

english, 1970

35

l-Type amino acid transporter 1 inhibitors inhibit tumor cell growth

Koji Oda, Noriko Hosoda, Hiroshi Endo, Kunio Saito, Kenji Tsujihara, Michio Yamamura, Takeshi Sakata, Naohiko Anzai, Michael F. Wempe, Yoshikatsu Kanai, Hitoshi Endou

Journal:

Year:

2010

Language:

english

File:

PDF, 442 KB

english, 2010

36

ChemInform Abstract: Water-Soluble Antitumor Agents. Part 1. Synthesis and Biological Activity of 6-S-Aminoacyloxymethyl Mercaptopurine Derivatives.

N. HARADA, M. HONGU, T. TANAKA, T. KASHIDA, N. NARASAKI, M. OHOHASHI, K. ODA, T. HASHIYAMA, K. TSUJIHARA

Journal:

Year:

1996

File:

PDF, 32 KB

1996

37

ChemInform Abstract: Synthesis and Biological Activity of O-Alkyl-3-N-aminoacyloxymethyl-5- fluoro-2′deoxyuridine Derivatives.

N. HARADA, M. HONGU, T. KAWAGUCHI, M. OHOHASHI, K. ODA, T. HASHIYAMA, K. TSUJIHARA

Journal:

Year:

1996

File:

PDF, 30 KB

1996

38

ChemInform Abstract: Na+-Glucose Cotransporter Inhibitors as Antidiabetics. Part 1. Synthesis and Pharmacological Properties of 4′-Dehydroxyphlorizin Derivatives Based on a New Concept.

K. TSUJIHARA, M. HONGU, K. SAITO, M. INAMASU, K. ARAKAWA, A. OKU, M. MATSUMOTO

Journal:

Year:

1996

File:

PDF, 31 KB

1996

39

Antidiabetic effect of T-1095, an inhibitor of Na+-glucose cotransporter, in neonatally streptozotocin-treated rats

Akira Oku, Kiichiro Ueta, Masao Nawano, Kenji Arakawa, Tomomi Kano-Ishihara, Mamoru Matsumoto, Akira Saito, Kenji Tsujihara, Motonobu Anai, Tomoichiro Asano

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 545 KB

english, 2000

40

Distribution of synaptosomal-associated protein 25 in nerve growth cones and reduction of neurite outgrowth by botulinum neurotoxin A without altering growth cone morphology in dorsal root ganglion neurons and PC-12 cells

T Morihara, A Mizoguchi, M Takahashi, S Kozaki, T Tsujihara, S Kawano, M Shirasu, T Ohmukai, M Kitada, K Kimura, S Okajima, K Tamai, Y Hirasawa, C Ide

Journal:

Year:

1999

Language:

english

File:

PDF, 3.42 MB

english, 1999

41

Deposition of diamond-like carbon films by excimer lasers using frozen acetylene

Hanabusa, M., Tsujihara, K.

Journal:

IEEE Journal of Selected Topics in Quantum Electronics

Year:

1995

Language:

english

File:

PDF, 367 KB

english, 1995

42

A Simple Preparation of Chloromethyl Esters of the Blocked Amino Acids

Harada, Naoyuki, Hongu, Mitsuya, Tanaka, Takashi, Kawaguchi, Takayuki, Hashiyama, Tomiki, Tsujihara, Kenji

Journal:

Synthetic Communications

Year:

1994

Language:

english

File:

PDF, 174 KB

english, 1994

43

Ethylidene glucose-substituted new analogue of streptozotocin cannot induce diabetes: Study on the basis of structure and activity relationship

Jun, Kawada, Miho, Okita, Mamoru, Nukatsuka, Kouhei, Toyooka, Shinsaku, Naito, Akihiro, Nabeshima, Kenji, Tsujihara, Yoshiyuki, Yoshimura, Mikio, Nishida

Journal:

Molecular and Cellular Endocrinology

Year:

1989

Language:

english

File:

PDF, 728 KB

english, 1989

44

A new class of nitrosoureas. 4. Synthesis and antitumor activity of disaccharide derivatives of 3,3-disubstituted 1-(2-chloroethyl)-1-nitrosoureas

Tsujihara, Kenji, Ozeki, Masakatsu, Morikawa, Tamio, Kawamori, Masatoshi, Akaike, Yukio, Arai, Yoshihisa

Journal:

Journal of Medicinal Chemistry

Year:

1982

Language:

english

File:

PDF, 747 KB

english, 1982

45

Pd II /Pd IV Catalytic Enantioselective Synthesis of Bicyclo[3.1.0]hexanes via Oxidative Cyclization of Enynes

Tsujihara, Tetsuya, Takenaka, Kazuhiro, Onitsuka, Kiyotaka, Hatanaka, Minoru, Sasai, Hiroaki

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 101 KB

english, 2009

46

Enantioselective Intramolecular Oxidative Aminocarbonylation of Alkenylureas Catalyzed by Palladium−Spiro Bis(isoxazoline) Complexes

Tsujihara, Tetsuya, Shinohara, Toshio, Takenaka, Kazuhiro, Takizawa, Shinobu, Onitsuka, Kiyotaka, Hatanaka, Minoru, Sasai, Hiroaki

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

47

Solid-Liquid Phase Transfer Catalyzed Novel Glycosylation Reaction of Phenols

Hongu, Mitsuya, Saito, Kunio, Tsujihara, Kenji

Journal:

Synthetic Communications

Year:

1999

Language:

english

File:

PDF, 241 KB

english, 1999

48

Diamond-like carbon films deposited by laser ablation using frozen acetylene targets

Hanabusa, Mitsugu, Tsujihara, Kiyohito

Journal:

Journal of Applied Physics

Year:

1995

Language:

english

File:

PDF, 555 KB

english, 1995

49

[IEEE Technical Digest. CLEO/Pacific Rim'95. The Pacific Rim Conference on Lasers and Electro-Optics - Chiba, Japan (10-14 July 1995)] Technical Digest. CLEO/Pacific Rim'95. The Pacific Rim Conference on Lasers and Electro-Optics - Reduction of particles in a-Si films deposited by laser ablation

Uchida, H., Tsujihara, K., Ishihara, S., Nakamura, N., Hasegawa, H., Hanabusa, M.

Year:

1995

Language:

english

File:

PDF, 159 KB

english, 1995

50

[IEEE 2005 Digest of Technical Papers. International Conference on Consumer Electronics, 2005. ICCE. - Las Vegas, NV, USA (2005.01.12-2005.01.12)] 2005 Digest of Technical Papers. International Conference on Consumer Electronics, 2005. ICCE. - Image quality improvement for plasma TV featuring adaptive controls in fully digitalized gray scale system

Kawahara, I., Tsujihara, S.

Year:

2005

Language:

english

File:

PDF, 182 KB

english, 2005